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Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
Designing innovative (nano)detection platforms, respecting their low-cost and fabrication simplicity, capable to chemically detect multiple target analytes by employing the same engineered device, is still a great challenge in the multiplexed biosensor development. In this scientific context, in the...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352805/ https://www.ncbi.nlm.nih.gov/pubmed/32471140 http://dx.doi.org/10.3390/nano10061025 |
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author | Susu, Laurentiu Campu, Andreea Astilean, Simion Focsan, Monica |
author_facet | Susu, Laurentiu Campu, Andreea Astilean, Simion Focsan, Monica |
author_sort | Susu, Laurentiu |
collection | PubMed |
description | Designing innovative (nano)detection platforms, respecting their low-cost and fabrication simplicity, capable to chemically detect multiple target analytes by employing the same engineered device, is still a great challenge in the multiplexed biosensor development. In this scientific context, in the current manuscript, we exploit the low-cost plasmonic calligraphy as a versatile approach to directly draw continuous plasmonic lines on Whatman paper using a regular ballpoint pen successively filled with two different anisotropic nanoparticles shapes (gold bipyramids—AuBPs and gold nanorods—AuNRs) as colloidal inks. After the efficient immobilization of the positively-charged AuBPs and AuNRs onto the paper fibres, proved by Scanning Electron Microscopy (SEM) investigations, the specificity of our as-calligraphed-paper platform is ensured by coating the selected lines with a thin layer of anionic poly(styrene sulfonate) polyelectrolyte, creating, consequently, a well-defined plasmonic array of charge-selective regions. Finally, the functionality of the well-isolated and as-miniaturized active plasmonic array is, subsequently, tested using the anionic Rose-Bengal and cationic Rhodamine 6G target analytes and proved by complementary dual optical “ON/OFF Switch” sensing (i.e. Surface-enhanced Raman Scattering sensing/metal-enhanced fluorescence sensing) onto the same plasmonic line, developing thus a simple multiplexed plasmonic array platform, which could further facilitate the well-desired biomarker detection in complex mixtures. |
format | Online Article Text |
id | pubmed-7352805 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73528052020-07-15 Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing Susu, Laurentiu Campu, Andreea Astilean, Simion Focsan, Monica Nanomaterials (Basel) Article Designing innovative (nano)detection platforms, respecting their low-cost and fabrication simplicity, capable to chemically detect multiple target analytes by employing the same engineered device, is still a great challenge in the multiplexed biosensor development. In this scientific context, in the current manuscript, we exploit the low-cost plasmonic calligraphy as a versatile approach to directly draw continuous plasmonic lines on Whatman paper using a regular ballpoint pen successively filled with two different anisotropic nanoparticles shapes (gold bipyramids—AuBPs and gold nanorods—AuNRs) as colloidal inks. After the efficient immobilization of the positively-charged AuBPs and AuNRs onto the paper fibres, proved by Scanning Electron Microscopy (SEM) investigations, the specificity of our as-calligraphed-paper platform is ensured by coating the selected lines with a thin layer of anionic poly(styrene sulfonate) polyelectrolyte, creating, consequently, a well-defined plasmonic array of charge-selective regions. Finally, the functionality of the well-isolated and as-miniaturized active plasmonic array is, subsequently, tested using the anionic Rose-Bengal and cationic Rhodamine 6G target analytes and proved by complementary dual optical “ON/OFF Switch” sensing (i.e. Surface-enhanced Raman Scattering sensing/metal-enhanced fluorescence sensing) onto the same plasmonic line, developing thus a simple multiplexed plasmonic array platform, which could further facilitate the well-desired biomarker detection in complex mixtures. MDPI 2020-05-27 /pmc/articles/PMC7352805/ /pubmed/32471140 http://dx.doi.org/10.3390/nano10061025 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Susu, Laurentiu Campu, Andreea Astilean, Simion Focsan, Monica Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing |
title | Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing |
title_full | Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing |
title_fullStr | Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing |
title_full_unstemmed | Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing |
title_short | Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing |
title_sort | calligraphed selective plasmonic arrays on paper platforms for complementary dual optical “on/off switch” sensing |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352805/ https://www.ncbi.nlm.nih.gov/pubmed/32471140 http://dx.doi.org/10.3390/nano10061025 |
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