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Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing

Designing innovative (nano)detection platforms, respecting their low-cost and fabrication simplicity, capable to chemically detect multiple target analytes by employing the same engineered device, is still a great challenge in the multiplexed biosensor development. In this scientific context, in the...

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Detalles Bibliográficos
Autores principales: Susu, Laurentiu, Campu, Andreea, Astilean, Simion, Focsan, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352805/
https://www.ncbi.nlm.nih.gov/pubmed/32471140
http://dx.doi.org/10.3390/nano10061025
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author Susu, Laurentiu
Campu, Andreea
Astilean, Simion
Focsan, Monica
author_facet Susu, Laurentiu
Campu, Andreea
Astilean, Simion
Focsan, Monica
author_sort Susu, Laurentiu
collection PubMed
description Designing innovative (nano)detection platforms, respecting their low-cost and fabrication simplicity, capable to chemically detect multiple target analytes by employing the same engineered device, is still a great challenge in the multiplexed biosensor development. In this scientific context, in the current manuscript, we exploit the low-cost plasmonic calligraphy as a versatile approach to directly draw continuous plasmonic lines on Whatman paper using a regular ballpoint pen successively filled with two different anisotropic nanoparticles shapes (gold bipyramids—AuBPs and gold nanorods—AuNRs) as colloidal inks. After the efficient immobilization of the positively-charged AuBPs and AuNRs onto the paper fibres, proved by Scanning Electron Microscopy (SEM) investigations, the specificity of our as-calligraphed-paper platform is ensured by coating the selected lines with a thin layer of anionic poly(styrene sulfonate) polyelectrolyte, creating, consequently, a well-defined plasmonic array of charge-selective regions. Finally, the functionality of the well-isolated and as-miniaturized active plasmonic array is, subsequently, tested using the anionic Rose-Bengal and cationic Rhodamine 6G target analytes and proved by complementary dual optical “ON/OFF Switch” sensing (i.e. Surface-enhanced Raman Scattering sensing/metal-enhanced fluorescence sensing) onto the same plasmonic line, developing thus a simple multiplexed plasmonic array platform, which could further facilitate the well-desired biomarker detection in complex mixtures.
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spelling pubmed-73528052020-07-15 Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing Susu, Laurentiu Campu, Andreea Astilean, Simion Focsan, Monica Nanomaterials (Basel) Article Designing innovative (nano)detection platforms, respecting their low-cost and fabrication simplicity, capable to chemically detect multiple target analytes by employing the same engineered device, is still a great challenge in the multiplexed biosensor development. In this scientific context, in the current manuscript, we exploit the low-cost plasmonic calligraphy as a versatile approach to directly draw continuous plasmonic lines on Whatman paper using a regular ballpoint pen successively filled with two different anisotropic nanoparticles shapes (gold bipyramids—AuBPs and gold nanorods—AuNRs) as colloidal inks. After the efficient immobilization of the positively-charged AuBPs and AuNRs onto the paper fibres, proved by Scanning Electron Microscopy (SEM) investigations, the specificity of our as-calligraphed-paper platform is ensured by coating the selected lines with a thin layer of anionic poly(styrene sulfonate) polyelectrolyte, creating, consequently, a well-defined plasmonic array of charge-selective regions. Finally, the functionality of the well-isolated and as-miniaturized active plasmonic array is, subsequently, tested using the anionic Rose-Bengal and cationic Rhodamine 6G target analytes and proved by complementary dual optical “ON/OFF Switch” sensing (i.e. Surface-enhanced Raman Scattering sensing/metal-enhanced fluorescence sensing) onto the same plasmonic line, developing thus a simple multiplexed plasmonic array platform, which could further facilitate the well-desired biomarker detection in complex mixtures. MDPI 2020-05-27 /pmc/articles/PMC7352805/ /pubmed/32471140 http://dx.doi.org/10.3390/nano10061025 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Susu, Laurentiu
Campu, Andreea
Astilean, Simion
Focsan, Monica
Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
title Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
title_full Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
title_fullStr Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
title_full_unstemmed Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
title_short Calligraphed Selective Plasmonic Arrays on Paper Platforms for Complementary Dual Optical “ON/OFF Switch” Sensing
title_sort calligraphed selective plasmonic arrays on paper platforms for complementary dual optical “on/off switch” sensing
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352805/
https://www.ncbi.nlm.nih.gov/pubmed/32471140
http://dx.doi.org/10.3390/nano10061025
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