Trans-Cinnamaldehyde Alleviates Amyloid-Beta Pathogenesis via the SIRT1-PGC1α-PPARγ Pathway in 5XFAD Transgenic Mice

Abnormal amyloid-β (Aβ) accumulation is the most significant feature of Alzheimer’s disease (AD). Among the several secretases involved in the generation of Aβ, β-secretase (BACE1) is the first rate-limiting enzyme in Aβ production that can be utilized to prevent the development of Aβ-related pathol...

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Detalles Bibliográficos
Autores principales: Do, Jimin, Kim, Namkwon, Jeon, Seung Ho, Gee, Min Sung, Ju, Yeon-Joo, Kim, Jong-Ho, Oh, Myung Sook, Lee, Jong Kil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352815/
https://www.ncbi.nlm.nih.gov/pubmed/32599846
http://dx.doi.org/10.3390/ijms21124492

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352815/
https://www.ncbi.nlm.nih.gov/pubmed/32599846
http://dx.doi.org/10.3390/ijms21124492

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