Cargando…

Fyn Tyrosine Kinase as Harmonizing Factor in Neuronal Functions and Dysfunctions

Fyn is a non-receptor or cytoplasmatic tyrosine kinase (TK) belonging to the Src family kinases (SFKs) involved in multiple transduction pathways in the central nervous system (CNS) including synaptic transmission, myelination, axon guidance, and oligodendrocyte formation. Almost one hundred years a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Matrone, Carmela, Petrillo, Federica, Nasso, Rosarita, Ferretti, Gabriella
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352836/ https://www.ncbi.nlm.nih.gov/pubmed/32580508 http://dx.doi.org/10.3390/ijms21124444

Ejemplares similares

Fyn Tyrosine Kinase Elicits Amyloid Precursor Protein Tyr682 Phosphorylation in Neurons from Alzheimer’s Disease Patients
por: Iannuzzi, Filomena, et al.
Publicado: (2020)

Challenges in LC–MS-based metabolomics for Alzheimer’s disease early detection: targeted approaches versus untargeted approaches
por: Reveglia, Pierluigi, et al.
Publicado: (2021)

Pyk2 is a Novel Tau Tyrosine Kinase that is Regulated by the Tyrosine Kinase Fyn
por: Li, Chuanzhou, et al.
Publicado: (2018)

Morphological Differentiation of Oligodendrocytes Requires Activation of Fyn Tyrosine Kinase
por: Osterhout, Donna J., et al.
Publicado: (1999)

Tyrosine Phosphorylation of Tau by the Src Family Kinases Lck and Fyn
por: Scales, Timothy ME, et al.
Publicado: (2011)

Involvement of Fyn tyrosine kinase in progression of cytokinesis of B lymphocyte progenitor
Publicado: (1996)

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes
Publicado: (1994)

The Src Family Tyrosine Kinase Fyn Regulates Natural Killer T Cell Development
por: Gadue, Paul, et al.
Publicado: (1999)

Fyn Tyrosine Kinase Increases Apolipoprotein E Receptor 2 Levels and Phosphorylation
por: Burrell, Teal C., et al.
Publicado: (2014)

Protein Tyrosine Phosphatase α (Ptpα) and Contactin Form a Novel Neuronal Receptor Complex Linked to the Intracellular Tyrosine Kinase Fyn
por: Zeng, Li, et al.
Publicado: (1999)

Roles of the Src Tyrosine Kinases Lck and Fyn in Regulating γδTCR Signal Strength
por: Laird, Renee M., et al.
Publicado: (2010)

Neuroblastoma Tyrosine Kinase Signaling Networks Involve FYN and LYN in Endosomes and Lipid Rafts
por: Palacios-Moreno, Juan, et al.
Publicado: (2015)

Fyn tyrosine kinase is a downstream mediator of Rho/PRK2 function in keratinocyte cell–cell adhesion
por: Calautti, Enzo, et al.
Publicado: (2002)

Tandem Mass Spectrometry as Strategy for the Selective Identification and Quantification of the Amyloid Precursor Protein Tyr682 Residue Phosphorylation Status in Human Blood Mononuclear Cells
por: Reveglia, Pierluigi, et al.
Publicado: (2021)

Suppression of protein tyrosine phosphatase N23 predisposes to breast tumorigenesis via activation of FYN kinase
por: Zhang, Siwei, et al.
Publicado: (2017)

Fyn kinase inhibition as a novel therapy for Alzheimer’s disease
por: Nygaard, Haakon B, et al.
Publicado: (2014)

A new paradigm for regulation of protein phosphatase 2A function via Src and Fyn kinase–mediated tyrosine phosphorylation
por: Sontag, Jean-Marie, et al.
Publicado: (2022)

Signal transduction in neurons: effects of cellular prion protein on fyn kinase and ERK1/2 kinase
por: Tomasi, Vittorio
Publicado: (2010)

Differential regulation of T cell antigen responsiveness by isoforms of the src-related tyrosine protein kinase p59fyn
Publicado: (1992)

Chromatin accessibility mapping of the striatum identifies tyrosine kinase FYN as a therapeutic target for heroin use disorder
por: Egervari, Gabor, et al.
Publicado: (2020)

Fyn Kinase Is Required for Optimal Humoral Responses
por: Chaimowitz, Natalia S., et al.
Publicado: (2013)

Fyn Kinase: A Potential Therapeutic Target in Acute Kidney Injury
por: Uddin, Md Jamal, et al.
Publicado: (2020)

Pharmacological inhibition of protein tyrosine kinases axl and fyn reduces TNF-α-induced endothelial inflammatory activation in vitro
por: Ellermann, Sophie F., et al.
Publicado: (2022)

Tyrosine Phosphorylation of Pyk2 Is Selectively Regulated by Fyn During TCR Signaling
por: Qian, Dapeng, et al.
Publicado: (1997)

Profiling the Expression and Prognostic Values of FYN, A Non-Receptor Tyrosine Kinase, in Different Histological Types of Epithelial Ovarian Cancer
por: Dankai, Wiyada, et al.
Publicado: (2023)

The SH2 domain is crucial for function of Fyn in neuronal migration and cortical lamination
por: Lu, Xi, et al.
Publicado: (2015)

The prion protein constitutively controls neuronal store-operated Ca(2+) entry through Fyn kinase
por: De Mario, Agnese, et al.
Publicado: (2015)

Fyn kinase regulates dopaminergic neuronal apoptosis in animal and cell models of high glucose (HG) treatment
por: Tan, Changhong, et al.
Publicado: (2021)

Fyn regeneration
por: Short, Ben
Publicado: (2012)

Reduced Surface Expression of Epithelial E-Cadherin Evoked by Interferon-Gamma Is Fyn Kinase-Dependent
por: Smyth, David, et al.
Publicado: (2012)

Nav1.7 is phosphorylated by Fyn tyrosine kinase which modulates channel expression and gating in a cell type-dependent manner
por: Li, Yangyang, et al.
Publicado: (2018)

Fyn-Mediated Paxillin Tyrosine 31 Phosphorylation Regulates Migration and Invasion of Breast Cancer Cells
por: Zhang, Ying, et al.
Publicado: (2023)

Activation of Src, Fyn and Yes non-receptor tyrosine kinases in keratinocytes expressing human papillomavirus (HPV) type 16 E7 oncoprotein
por: Szalmás, Anita, et al.
Publicado: (2013)

Regulation of natural cytotoxicity by the adaptor SAP and the Src-related kinase Fyn
por: Bloch-Queyrat, Coralie, et al.
Publicado: (2005)

CD36 and Fyn Kinase Mediate Malaria-Induced Lung Endothelial Barrier Dysfunction in Mice Infected with Plasmodium berghei
por: Anidi, Ifeanyi U., et al.
Publicado: (2013)

An Essential Role of Fyn in the Modulation of Metabotropic Glutamate Receptor 1 in Neurons
por: Jin, Dao-Zhong, et al.
Publicado: (2017)

Nuclear Functions of the Tyrosine Kinase Src
por: Bagnato, Giulia, et al.
Publicado: (2020)

Mechanisms of disease-modifying effect of saracatinib (AZD0530), a Src/Fyn tyrosine kinase inhibitor, in the rat kainate model of temporal lobe epilepsy
por: Sharma, Shaunik, et al.
Publicado: (2021)

Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas
por: Palomero, Teresa, et al.
Publicado: (2014)

Differential activation of Fyn kinase distinguishes saturated and unsaturated fats in mouse macrophages
por: Tarabra, Elena, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_5tr64q459vdetdv4ri1k9srq0b