The Deubiquitinase USP4 Stabilizes Twist1 Protein to Promote Lung Cancer Cell Stemness

Lung cancer stem cells (CSCs) play a pivotal role in tumor development, drug resistance, metastasis and recurrence of lung cancer. Thus, it is of great importance to study the mechanism by which CSCs are regulated. In this study, we demonstrate that the deubiquitinase USP4 is critically important in...

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Detalles Bibliográficos
Autores principales: Li, Fengtian, Hu, Qingyong, He, Tao, Xu, Jing, Yi, Yong, Xie, Siyi, Ding, Liangping, Fu, Mengyuan, Guo, Rongtian, Xiao, Zhi-Xiong Jim, Niu, Mengmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352958/
https://www.ncbi.nlm.nih.gov/pubmed/32549341
http://dx.doi.org/10.3390/cancers12061582

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