Triarylpyridine Compounds and Chloroquine Act in Concert to Trigger Lysosomal Membrane Permeabilization and Cell Death in Cancer Cells

Lysosomes play a key role in regulating cell death in response to cancer therapies, yet little is known on the possible role of lysosomes in the therapeutic efficacy of G-quadruplex DNA ligands (G4L) in cancer cells. Here, we investigate the relationship between the modulation of lysosomal membrane...

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Detalles Bibliográficos
Autores principales: Beauvarlet, Jennifer, Nath Das, Rabindra, Alvarez-Valadez, Karla, Martins, Isabelle, Muller, Alexandra, Darbo, Elodie, Richard, Elodie, Soubeyran, Pierre, Kroemer, Guido, Guillon, Jean, Mergny, Jean-Louis, Djavaheri-Mergny, Mojgan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352983/
https://www.ncbi.nlm.nih.gov/pubmed/32570977
http://dx.doi.org/10.3390/cancers12061621

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7352983/
https://www.ncbi.nlm.nih.gov/pubmed/32570977
http://dx.doi.org/10.3390/cancers12061621

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