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Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
Limited knowledge is available on dietary patterns and bladder cancer risk. We analyzed data from an Italian case-control study carried out between 2003 and 2014, including 690 incident bladder cancer cases and 665 hospital-controls. We derived nutrient-based dietary patterns applying principal comp...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353000/ https://www.ncbi.nlm.nih.gov/pubmed/32481645 http://dx.doi.org/10.3390/nu12061584 |
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author | Edefonti, Valeria La Vecchia, Carlo Di Maso, Matteo Crispo, Anna Polesel, Jerry Libra, Massimo Parpinel, Maria Serraino, Diego Ferraroni, Monica Bravi, Francesca |
author_facet | Edefonti, Valeria La Vecchia, Carlo Di Maso, Matteo Crispo, Anna Polesel, Jerry Libra, Massimo Parpinel, Maria Serraino, Diego Ferraroni, Monica Bravi, Francesca |
author_sort | Edefonti, Valeria |
collection | PubMed |
description | Limited knowledge is available on dietary patterns and bladder cancer risk. We analyzed data from an Italian case-control study carried out between 2003 and 2014, including 690 incident bladder cancer cases and 665 hospital-controls. We derived nutrient-based dietary patterns applying principal component factor analysis on 28 selected nutrients. We categorized factor scores according to quartiles, and estimated the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) through logistic regression models, adjusted for major confounding factors. We identified four dietary patterns named “Animal products”, “Vitamins and fiber”, “Starch-rich”, and “Animal unsaturated fatty acids”. We found an inverse association between the “Vitamins and fiber” pattern and bladder cancer (OR = 0.70, 95% CI: 0.48–0.99, IV versus I quartile category). Inverse relationships of borderline significance were also found for the “Animal products” and the “Animal unsaturated fatty acids” dietary patterns. No significant association was evident for the “Starch-rich” pattern. The current study allowed us to identify major dietary patterns in this Italian population. Our study confirms available evidence and shows that scoring high on a fruit-and-vegetables pattern provides beneficial effects on bladder cancer risk. |
format | Online Article Text |
id | pubmed-7353000 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-73530002020-07-15 Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy Edefonti, Valeria La Vecchia, Carlo Di Maso, Matteo Crispo, Anna Polesel, Jerry Libra, Massimo Parpinel, Maria Serraino, Diego Ferraroni, Monica Bravi, Francesca Nutrients Article Limited knowledge is available on dietary patterns and bladder cancer risk. We analyzed data from an Italian case-control study carried out between 2003 and 2014, including 690 incident bladder cancer cases and 665 hospital-controls. We derived nutrient-based dietary patterns applying principal component factor analysis on 28 selected nutrients. We categorized factor scores according to quartiles, and estimated the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) through logistic regression models, adjusted for major confounding factors. We identified four dietary patterns named “Animal products”, “Vitamins and fiber”, “Starch-rich”, and “Animal unsaturated fatty acids”. We found an inverse association between the “Vitamins and fiber” pattern and bladder cancer (OR = 0.70, 95% CI: 0.48–0.99, IV versus I quartile category). Inverse relationships of borderline significance were also found for the “Animal products” and the “Animal unsaturated fatty acids” dietary patterns. No significant association was evident for the “Starch-rich” pattern. The current study allowed us to identify major dietary patterns in this Italian population. Our study confirms available evidence and shows that scoring high on a fruit-and-vegetables pattern provides beneficial effects on bladder cancer risk. MDPI 2020-05-28 /pmc/articles/PMC7353000/ /pubmed/32481645 http://dx.doi.org/10.3390/nu12061584 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Edefonti, Valeria La Vecchia, Carlo Di Maso, Matteo Crispo, Anna Polesel, Jerry Libra, Massimo Parpinel, Maria Serraino, Diego Ferraroni, Monica Bravi, Francesca Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy |
title | Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy |
title_full | Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy |
title_fullStr | Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy |
title_full_unstemmed | Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy |
title_short | Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy |
title_sort | association between nutrient-based dietary patterns and bladder cancer in italy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353000/ https://www.ncbi.nlm.nih.gov/pubmed/32481645 http://dx.doi.org/10.3390/nu12061584 |
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