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Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy

Limited knowledge is available on dietary patterns and bladder cancer risk. We analyzed data from an Italian case-control study carried out between 2003 and 2014, including 690 incident bladder cancer cases and 665 hospital-controls. We derived nutrient-based dietary patterns applying principal comp...

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Autores principales: Edefonti, Valeria, La Vecchia, Carlo, Di Maso, Matteo, Crispo, Anna, Polesel, Jerry, Libra, Massimo, Parpinel, Maria, Serraino, Diego, Ferraroni, Monica, Bravi, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353000/
https://www.ncbi.nlm.nih.gov/pubmed/32481645
http://dx.doi.org/10.3390/nu12061584
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author Edefonti, Valeria
La Vecchia, Carlo
Di Maso, Matteo
Crispo, Anna
Polesel, Jerry
Libra, Massimo
Parpinel, Maria
Serraino, Diego
Ferraroni, Monica
Bravi, Francesca
author_facet Edefonti, Valeria
La Vecchia, Carlo
Di Maso, Matteo
Crispo, Anna
Polesel, Jerry
Libra, Massimo
Parpinel, Maria
Serraino, Diego
Ferraroni, Monica
Bravi, Francesca
author_sort Edefonti, Valeria
collection PubMed
description Limited knowledge is available on dietary patterns and bladder cancer risk. We analyzed data from an Italian case-control study carried out between 2003 and 2014, including 690 incident bladder cancer cases and 665 hospital-controls. We derived nutrient-based dietary patterns applying principal component factor analysis on 28 selected nutrients. We categorized factor scores according to quartiles, and estimated the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) through logistic regression models, adjusted for major confounding factors. We identified four dietary patterns named “Animal products”, “Vitamins and fiber”, “Starch-rich”, and “Animal unsaturated fatty acids”. We found an inverse association between the “Vitamins and fiber” pattern and bladder cancer (OR = 0.70, 95% CI: 0.48–0.99, IV versus I quartile category). Inverse relationships of borderline significance were also found for the “Animal products” and the “Animal unsaturated fatty acids” dietary patterns. No significant association was evident for the “Starch-rich” pattern. The current study allowed us to identify major dietary patterns in this Italian population. Our study confirms available evidence and shows that scoring high on a fruit-and-vegetables pattern provides beneficial effects on bladder cancer risk.
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spelling pubmed-73530002020-07-15 Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy Edefonti, Valeria La Vecchia, Carlo Di Maso, Matteo Crispo, Anna Polesel, Jerry Libra, Massimo Parpinel, Maria Serraino, Diego Ferraroni, Monica Bravi, Francesca Nutrients Article Limited knowledge is available on dietary patterns and bladder cancer risk. We analyzed data from an Italian case-control study carried out between 2003 and 2014, including 690 incident bladder cancer cases and 665 hospital-controls. We derived nutrient-based dietary patterns applying principal component factor analysis on 28 selected nutrients. We categorized factor scores according to quartiles, and estimated the odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) through logistic regression models, adjusted for major confounding factors. We identified four dietary patterns named “Animal products”, “Vitamins and fiber”, “Starch-rich”, and “Animal unsaturated fatty acids”. We found an inverse association between the “Vitamins and fiber” pattern and bladder cancer (OR = 0.70, 95% CI: 0.48–0.99, IV versus I quartile category). Inverse relationships of borderline significance were also found for the “Animal products” and the “Animal unsaturated fatty acids” dietary patterns. No significant association was evident for the “Starch-rich” pattern. The current study allowed us to identify major dietary patterns in this Italian population. Our study confirms available evidence and shows that scoring high on a fruit-and-vegetables pattern provides beneficial effects on bladder cancer risk. MDPI 2020-05-28 /pmc/articles/PMC7353000/ /pubmed/32481645 http://dx.doi.org/10.3390/nu12061584 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Edefonti, Valeria
La Vecchia, Carlo
Di Maso, Matteo
Crispo, Anna
Polesel, Jerry
Libra, Massimo
Parpinel, Maria
Serraino, Diego
Ferraroni, Monica
Bravi, Francesca
Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
title Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
title_full Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
title_fullStr Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
title_full_unstemmed Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
title_short Association between Nutrient-Based Dietary Patterns and Bladder Cancer in Italy
title_sort association between nutrient-based dietary patterns and bladder cancer in italy
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353000/
https://www.ncbi.nlm.nih.gov/pubmed/32481645
http://dx.doi.org/10.3390/nu12061584
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