Cargando…

Oral Bioavailability Enhancement of Raloxifene with Nanostructured Lipid Carriers

Raloxifene hydrochloride (RLX) shows poor bioavailability (<2%), high inter-patient variability and extensive gut metabolism (>90%). The objective of this study was to develop nanostructured lipid carriers (NLCs) for RLX to enhance its bioavailability. The NLC formulations were produced with g...

Descripción completa

Detalles Bibliográficos
Autores principales:	Murthy, Aditya, Rao Ravi, Punna, Kathuria, Himanshu, Malekar, Shrinivas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353254/ https://www.ncbi.nlm.nih.gov/pubmed/32486508 http://dx.doi.org/10.3390/nano10061085

Ejemplares similares

Development and characterization of solid lipid nanoparticles for enhancement of oral bioavailability of Raloxifene
por: Patel, B. Divyakant, et al.
Publicado: (2012)

Development and Evaluation of Solid Lipid Nanoparticles of Raloxifene Hydrochloride for Enhanced Bioavailability
por: Kushwaha, Anand Kumar, et al.
Publicado: (2013)

Improvement of oral bioavailability of lovastatin by using nanostructured lipid carriers
por: Zhou, Jun, et al.
Publicado: (2015)

Enhancing Oral Bioavailability and Brain Biodistribution of Perillyl Alcohol Using Nanostructured Lipid Carriers
por: Peczek, Samila Horst, et al.
Publicado: (2023)

Tailoring Apixaban in Nanostructured Lipid Carrier Enhancing Its Oral Bioavailability and Anticoagulant Activity
por: Zaky, Mohamed F., et al.
Publicado: (2022)

Bioadhesive polymer/lipid hybrid nanoparticles as oral delivery system of raloxifene with enhancive intestinal retention and bioavailability
por: Du, Xinhui, et al.
Publicado: (2021)

Oral bioavailability enhancement of agomelatine by loading into nanostructured lipid carriers: Peyer’s patch targeting approach
por: Prajapati, Jagruti B, et al.
Publicado: (2018)

Augmented Oral Bioavailability and Prokinetic Activity of Levosulpiride Delivered in Nanostructured Lipid Carriers
por: Arif, Sadia Tabassam, et al.
Publicado: (2022)

Nanostructured lipid carriers: An emerging platform for improving oral bioavailability of lipophilic drugs
por: Khan, Saba, et al.
Publicado: (2015)

EGCG intestinal absorption and oral bioavailability enhancement using folic acid-functionalized nanostructured lipid carriers
por: Granja, Andreia, et al.
Publicado: (2019)

Improvement of fluvastatin bioavailability by loading on nanostructured lipid carriers
por: El-Helw, Abdel-Rahim M, et al.
Publicado: (2015)

Enhancing the Oral Bioavailability of Candesartan Cilexetil Loaded Nanostructured Lipid Carriers: In Vitro Characterization and Absorption in Rats after Oral Administration
por: Anwar, Walid, et al.
Publicado: (2020)

Nanostructured Lipid Carriers to Enhance the Bioavailability and Solubility of Ranolazine: Statistical Optimization and Pharmacological Evaluations
por: Unnisa, Aziz, et al.
Publicado: (2023)

Systemic Design and Evaluation of Ticagrelor-Loaded Nanostructured Lipid Carriers for Enhancing Bioavailability and Antiplatelet Activity
por: Son, Gi-Ho, et al.
Publicado: (2019)

Improving intestinal absorption and oral bioavailability of curcumin via taurocholic acid-modified nanostructured lipid carriers
por: Tian, Cihui, et al.
Publicado: (2017)

Nanostructured Lipid Carrier-Based Codelivery of Raloxifene and Naringin: Formulation, Optimization, In Vitro, Ex Vivo, In Vivo Assessment, and Acute Toxicity Studies
por: Alhalmi, Abdulsalam, et al.
Publicado: (2022)

A PEGylated Nanostructured Lipid Carrier for Enhanced Oral Delivery of Antibiotics
por: Alavi, Seyed Ebrahim, et al.
Publicado: (2022)

N-acetyl-L-cysteine functionalized nanostructured lipid carrier for improving oral bioavailability of curcumin: preparation, in vitro and in vivo evaluations
por: Tian, Cihui, et al.
Publicado: (2017)

Formulation and Evaluation of a Self-Microemulsifying Drug Delivery System of Raloxifene with Improved Solubility and Oral Bioavailability
por: Ansari, Muhammad Mohsin, et al.
Publicado: (2023)

Nanostructured lipid carriers: versatile oral delivery vehicle
por: Poonia, Neelam, et al.
Publicado: (2016)

Freeze-Dried Lopinavir-Loaded Nanostructured Lipid Carriers for Enhanced Cellular Uptake and Bioavailability: Statistical Optimization, in Vitro and in Vivo Evaluations
por: Khan, Arshad Ali, et al.
Publicado: (2019)

Simple, Rapid and Validated LC Determination of Lopinavir in Rat Plasma and its Application in Pharmacokinetic Studies
por: Vats, Rahul, et al.
Publicado: (2011)

Human serum albumin-based nanoparticles alter raloxifene administration and improve bioavailability
por: Yang, Shu-Jyuan, et al.
Publicado: (2022)

Nanostructured Lipid Carriers Loaded with Baicalin: An Efficient Carrier for Enhanced Antidiabetic Effects
por: Shi, Feng, et al.
Publicado: (2016)

Nanostructured Lipid Carriers Can Enhance Oral Absorption of Khellin, a Natural Pleiotropic Molecule
por: Vanti, Giulia, et al.
Publicado: (2021)

Raloxifene/SBE-β-CD Inclusion Complexes Formulated into Nanoparticles with Chitosan to Overcome the Absorption Barrier for Bioavailability Enhancement
por: Wang, Zaihua, et al.
Publicado: (2018)

Preparation and characterization of nimodipine-loaded nanostructured lipid systems for enhanced solubility and bioavailability
por: Teng, Zaijin, et al.
Publicado: (2018)

Antineoplastics Encapsulated in Nanostructured Lipid Carriers
por: Rodrigues da Silva, Gustavo Henrique, et al.
Publicado: (2021)

Design, Characterization and Pharmacokinetic–Pharmacodynamic Evaluation of Poloxamer and Kappa-Carrageenan-Based Dual-Responsive In Situ Gel of Nebivolol for Treatment of Open-Angle Glaucoma
por: Rawat, Pradeep Singh, et al.
Publicado: (2023)

Supersaturated Lipid-Based Formulations to Enhance the Oral Bioavailability of Venetoclax
por: Koehl, Niklas J., et al.
Publicado: (2020)

Strategies to enhance oral delivery of amphotericin B: a comparison of uncoated and enteric-coated nanostructured lipid carriers
por: Nimtrakul, Pataranapa, et al.
Publicado: (2020)

Development of novel rosuvastatin nanostructured lipid carriers for oral delivery in an animal model
por: Li, Jun, et al.
Publicado: (2018)

Berberine-Loaded Nanostructured Lipid Carriers Enhance the Treatment of Ulcerative Colitis
por: Deng, Jianping, et al.
Publicado: (2020)

A Non-Lipolysis Nanoemulsion Improved Oral Bioavailability by Reducing the First-Pass Metabolism of Raloxifene, and Related Absorption Mechanisms Being Studied
por: Ye, Jing-Yi, et al.
Publicado: (2020)

Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge
por: Arzani, Gelareh, et al.
Publicado: (2015)

Atorvastatin-loaded nanostructured lipid carriers (NLCs): strategy to overcome oral delivery drawbacks
por: Elmowafy, Mohammed, et al.
Publicado: (2017)

Nanostructured Lipid Carriers: A potential drug carrier for cancer chemotherapy
por: Selvamuthukumar, Subramanian, et al.
Publicado: (2012)

Effect of cell-penetrating peptide-coated nanostructured lipid carriers on the oral absorption of tripterine
por: Chen, Yan, et al.
Publicado: (2012)

Catan-ionic hybrid lipidic nano-carriers for enhanced bioavailability and anti-tumor efficacy of chemodrugs
por: Liu, Bilin, et al.
Publicado: (2017)

Stability enhancement of lycopene in Citrullus lanatus extract via nanostructured lipid carriers
por: Sirikhet, Jutiporn, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_u12stgdrqti44j8uv0mt5kivpo