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Review of Copper and Copper Nanoparticle Toxicity in Fish

This review summarizes the present knowledge on the toxicity of copper and copper nanoparticles (CuNPs) to various fish species. In previous decades, the excessive usage of metal and metallic nanoparticles has increased significantly, increasing the probability of the accumulation and discharge of m...

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Autores principales: Malhotra, Nemi, Ger, Tzong-Rong, Uapipatanakul, Boontida, Huang, Jong-Chin, Chen, Kelvin H.-C., Hsiao, Chung-Der
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353310/
https://www.ncbi.nlm.nih.gov/pubmed/32517348
http://dx.doi.org/10.3390/nano10061126
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author Malhotra, Nemi
Ger, Tzong-Rong
Uapipatanakul, Boontida
Huang, Jong-Chin
Chen, Kelvin H.-C.
Hsiao, Chung-Der
author_facet Malhotra, Nemi
Ger, Tzong-Rong
Uapipatanakul, Boontida
Huang, Jong-Chin
Chen, Kelvin H.-C.
Hsiao, Chung-Der
author_sort Malhotra, Nemi
collection PubMed
description This review summarizes the present knowledge on the toxicity of copper and copper nanoparticles (CuNPs) to various fish species. In previous decades, the excessive usage of metal and metallic nanoparticles has increased significantly, increasing the probability of the accumulation and discharge of metals in various trophic levels of the environment. Due to these concerns, it is important to understand the toxicity mechanisms of metals and metallic nanoparticles before they lead to unhealthy effects on human health. In this review paper, we specifically focus on the effect of metal copper and CuNPs on different fish organs under different physiochemical parameters of various water bodies. Nowadays, different forms of copper have distinctive and specific usages, e.g., copper sulfate is a well-established pesticide which is used to control the growth of algae in lakes and ponds. Deactivating the fungi enzymes prevents fungal spores from germinating. This process of deactivation is achieved via the free cupric ions, which are established as the most toxic forms of copper. Complexes of copper with other ligands may or may not be bioavailable for use in aquatic organisms. On the other hand, CuNPs have shown cost-effectiveness and numerous promising uses, but the toxicity and availability of copper in a nanoparticle form is largely unknown, Additionally, physiochemical factors such as the hardness of the water, alkalinity, presence of inorganic and organic ligands, levels of pH, and temperature in various different water bodies affect the toxicity caused by copper and CuNPs. However, comprehensive knowledge and data regarding the pattern of toxicity for copper metal ions and CuNPs in marine organisms is still limited. In this review, we carry out a critical analysis of the availability of the toxicological profiles of copper metal ions and CuNPs for different fishes in order to understand the toxicity mechanisms of copper and CuNPs. We believe that this review will provide valuable information on the toxicological profile of copper, which will further help in devising safe guidelines for the usage of copper and CuNPs in a sustainable manner.
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spelling pubmed-73533102020-07-15 Review of Copper and Copper Nanoparticle Toxicity in Fish Malhotra, Nemi Ger, Tzong-Rong Uapipatanakul, Boontida Huang, Jong-Chin Chen, Kelvin H.-C. Hsiao, Chung-Der Nanomaterials (Basel) Review This review summarizes the present knowledge on the toxicity of copper and copper nanoparticles (CuNPs) to various fish species. In previous decades, the excessive usage of metal and metallic nanoparticles has increased significantly, increasing the probability of the accumulation and discharge of metals in various trophic levels of the environment. Due to these concerns, it is important to understand the toxicity mechanisms of metals and metallic nanoparticles before they lead to unhealthy effects on human health. In this review paper, we specifically focus on the effect of metal copper and CuNPs on different fish organs under different physiochemical parameters of various water bodies. Nowadays, different forms of copper have distinctive and specific usages, e.g., copper sulfate is a well-established pesticide which is used to control the growth of algae in lakes and ponds. Deactivating the fungi enzymes prevents fungal spores from germinating. This process of deactivation is achieved via the free cupric ions, which are established as the most toxic forms of copper. Complexes of copper with other ligands may or may not be bioavailable for use in aquatic organisms. On the other hand, CuNPs have shown cost-effectiveness and numerous promising uses, but the toxicity and availability of copper in a nanoparticle form is largely unknown, Additionally, physiochemical factors such as the hardness of the water, alkalinity, presence of inorganic and organic ligands, levels of pH, and temperature in various different water bodies affect the toxicity caused by copper and CuNPs. However, comprehensive knowledge and data regarding the pattern of toxicity for copper metal ions and CuNPs in marine organisms is still limited. In this review, we carry out a critical analysis of the availability of the toxicological profiles of copper metal ions and CuNPs for different fishes in order to understand the toxicity mechanisms of copper and CuNPs. We believe that this review will provide valuable information on the toxicological profile of copper, which will further help in devising safe guidelines for the usage of copper and CuNPs in a sustainable manner. MDPI 2020-06-07 /pmc/articles/PMC7353310/ /pubmed/32517348 http://dx.doi.org/10.3390/nano10061126 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Malhotra, Nemi
Ger, Tzong-Rong
Uapipatanakul, Boontida
Huang, Jong-Chin
Chen, Kelvin H.-C.
Hsiao, Chung-Der
Review of Copper and Copper Nanoparticle Toxicity in Fish
title Review of Copper and Copper Nanoparticle Toxicity in Fish
title_full Review of Copper and Copper Nanoparticle Toxicity in Fish
title_fullStr Review of Copper and Copper Nanoparticle Toxicity in Fish
title_full_unstemmed Review of Copper and Copper Nanoparticle Toxicity in Fish
title_short Review of Copper and Copper Nanoparticle Toxicity in Fish
title_sort review of copper and copper nanoparticle toxicity in fish
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353310/
https://www.ncbi.nlm.nih.gov/pubmed/32517348
http://dx.doi.org/10.3390/nano10061126
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