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Protocatechuic Acid Extends Survival, Improves Motor Function, Diminishes Gliosis, and Sustains Neuromuscular Junctions in the hSOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a devastating disorder characterized by motor neuron apoptosis and subsequent skeletal muscle atrophy caused by oxidative and nitrosative stress, mitochondrial dysfunction, and neuroinflammation. Anthocyanins are polyphenolic compounds found in berries that pos...
Autores principales: | Koza, Lilia A., Winter, Aimee N., Holsopple, Jessica, Baybayon-Grandgeorge, Angela N., Pena, Claudia, Olson, Jeffrey R., Mazzarino, Randall C., Patterson, David, Linseman, Daniel A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353311/ https://www.ncbi.nlm.nih.gov/pubmed/32570926 http://dx.doi.org/10.3390/nu12061824 |
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