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Induction of Proteasome Subunit Low Molecular Weight Protein (LMP)-2 Is Required to Induce Active Remodeling in Adult Rat Ventricular Cardiomyocytes

Isolated adult rat ventricular cardiomyocytes (ARVC) adapt to the two-dimensional surface of culture dishes once they are isolated from the three-dimensional heart tissue. This process mimics aspects of cardiac adaptation to pressure overload and requires an initial breakdown of sarcomeric structure...

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Detalles Bibliográficos
Autores principales: Petersen, Antonia, Kutsche, Hanna Sarah, Nippert, Franziska, Schreckenberg, Rolf, Schulz, Rainer, Schlüter, Klaus-Dieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353499/
https://www.ncbi.nlm.nih.gov/pubmed/32370048
http://dx.doi.org/10.3390/medsci8020021