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Induction of Proteasome Subunit Low Molecular Weight Protein (LMP)-2 Is Required to Induce Active Remodeling in Adult Rat Ventricular Cardiomyocytes
Isolated adult rat ventricular cardiomyocytes (ARVC) adapt to the two-dimensional surface of culture dishes once they are isolated from the three-dimensional heart tissue. This process mimics aspects of cardiac adaptation to pressure overload and requires an initial breakdown of sarcomeric structure...
Autores principales: | Petersen, Antonia, Kutsche, Hanna Sarah, Nippert, Franziska, Schreckenberg, Rolf, Schulz, Rainer, Schlüter, Klaus-Dieter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353499/ https://www.ncbi.nlm.nih.gov/pubmed/32370048 http://dx.doi.org/10.3390/medsci8020021 |
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