LncRNA HOTAIR-mediated MTHFR methylation inhibits 5-fluorouracil sensitivity in esophageal cancer cells

BACKGROUND: Esophageal cancer (EC) represents one of the most aggressive digestive neoplasms globally, with marked geographical variations in morbidity and mortality. Chemoprevention is a promising approach for cancer therapy, while acquired chemoresistance is a major obstacle impeding the success o...

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Detalles Bibliográficos
Autores principales: Zhang, Shuyao, Zheng, Fuchun, Zhang, Liqun, Huang, Zuojun, Huang, Xiaoshan, Pan, Zhen, Chen, Shuang, Xu, Chenchen, Jiang, Yi, Gu, Shuyi, Zhao, Chengkuan, Zhang, Qiuzhen, Shi, Ganggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353690/
https://www.ncbi.nlm.nih.gov/pubmed/32653028
http://dx.doi.org/10.1186/s13046-020-01610-1

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