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Detecting fitness epistasis in recently admixed populations with genome-wide data

BACKGROUND: Fitness epistasis, the interaction effect of genes at different loci on fitness, makes an important contribution to adaptive evolution. Although fitness interaction evidence has been observed in model organisms, it is more difficult to detect and remains poorly understood in human popula...

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Detalles Bibliográficos
Autores principales: Ni, Xumin, Zhou, Mengshi, Wang, Heming, He, Karen Y., Broeckel, Uli, Hanis, Craig, Kardia, Sharon, Redline, Susan, Cooper, Richard S., Tang, Hua, Zhu, Xiaofeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353720/
https://www.ncbi.nlm.nih.gov/pubmed/32652930
http://dx.doi.org/10.1186/s12864-020-06874-7