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Higher sensitivity of female cells to ethanol: methylation of DNA lowers Cyp2e1, generating more ROS

BACKGROUND: Cells taken from mouse embryos before sex differentiation respond to insults according to their chromosomal sex, a difference traceable to differential methylation. We evaluated the mechanism for this difference in the controlled situation of their response to ethanol. METHODS: We evalua...

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Detalles Bibliográficos
Autores principales:	Penaloza, Carlos G., Cruz, Mayra, Germain, Gabrielle, Jabeen, Sidra, Javdan, Mohammad, Lockshin, Richard A., Zakeri, Zahra
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353761/ https://www.ncbi.nlm.nih.gov/pubmed/32653010 http://dx.doi.org/10.1186/s12964-020-00616-8

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