Cargando…
Controlled Human Infection With Bordetella pertussis Induces Asymptomatic, Immunizing Colonization
BACKGROUND: Bordetella pertussis is among the leading causes of vaccine-preventable deaths and morbidity globally. Human asymptomatic carriage as a reservoir for community transmission of infections might be a target of future vaccine strategies, but has not been demonstrated. Our objective was to d...
Autores principales: | de Graaf, Hans, Ibrahim, Muktar, Hill, Alison R, Gbesemete, Diane, Vaughan, Andrew T, Gorringe, Andrew, Preston, Andrew, Buisman, Annemarie M, Faust, Saul N, Kester, Kent E, Berbers, Guy A M, Diavatopoulos, Dimitri A, Read, Robert C |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353841/ https://www.ncbi.nlm.nih.gov/pubmed/31562530 http://dx.doi.org/10.1093/cid/ciz840 |
Ejemplares similares
-
167. A Bordetella pertussis Human Challenge Model Induces Immunizing Colonization in the Absence of Symptoms
por: Graaf, Hans De, et al.
Publicado: (2018) -
Investigating Bordetella pertussis colonisation and immunity: protocol for an inpatient controlled human infection model
por: de Graaf, Hans, et al.
Publicado: (2017) -
Bordetella pertussis isolates vary in their interactions with human complement components
por: Brookes, Charlotte, et al.
Publicado: (2018) -
Protocol for a controlled human infection with genetically modified Neisseria lactamica expressing the meningococcal vaccine antigen NadA: a potent new technique for experimental medicine
por: Gbesemete, Diane, et al.
Publicado: (2019) -
A qPCR assay for Bordetella pertussis cells that enumerates both live and dead bacteria
por: Ramkissoon, Stacy, et al.
Publicado: (2020)