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Penetrance of Breast and Ovarian Cancer in Women Who Carry a BRCA1/2 Mutation and Do Not Use Risk-Reducing Salpingo-Oophorectomy: An Updated Meta-Analysis
BACKGROUND: Use of risk-reducing Salpingo-oophorectomy (RRSO) substantially reduces the risk of ovarian and breast cancer for women who carry a BRCA1/2 mutation. It is important to adjust for RRSO use in the estimation of BRCA1/2 penetrance of breast and ovarian cancer. METHODS: We searched PubMed f...
Autores principales: | Chen, Jinbo, Bae, Eunchan, Zhang, Lingjiao, Hughes, Kevin, Parmigiani, Giovanni, Braun, Danielle, Rebbeck, Timothy R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7353955/ https://www.ncbi.nlm.nih.gov/pubmed/32676552 http://dx.doi.org/10.1093/jncics/pkaa029 |
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