Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy

Minimal hepatic encephalopathy (MHE), which shows mild cognitive impairment, is a subtle complication of cirrhosis that has been shown to affect daily functioning and quality of life. However, until 2014, relevant guidelines do not give much attention to the diagnosis and treatment of MHE, resulting...

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Detalles Bibliográficos
Autores principales: Han, Weijia, Zhang, Huanqian, Han, Ying, Duan, Zhongping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354280/
https://www.ncbi.nlm.nih.gov/pubmed/32495311
http://dx.doi.org/10.1007/s11011-020-00539-w
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author Han, Weijia
Zhang, Huanqian
Han, Ying
Duan, Zhongping
author_facet Han, Weijia
Zhang, Huanqian
Han, Ying
Duan, Zhongping
author_sort Han, Weijia
collection PubMed
description Minimal hepatic encephalopathy (MHE), which shows mild cognitive impairment, is a subtle complication of cirrhosis that has been shown to affect daily functioning and quality of life. However, until 2014, relevant guidelines do not give much attention to the diagnosis and treatment of MHE, resulting in patients being ignored and denied the benefits of treatment. In this review, we summarize recent cognition-based research about (1) alteration of nerve cells, including astrocytes, microglial cells and neurons, in mild cognitive impairment in MHE; (2) comparison of methods in detecting cognitive impairment in MHE; and (3) comparison of methods for therapy of cognitive impairment in MHE. We hope to provide information about diagnosis and treatment of cognitive impairment in patients with MHE.
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spelling pubmed-73542802020-07-14 Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy Han, Weijia Zhang, Huanqian Han, Ying Duan, Zhongping Metab Brain Dis Review Article Minimal hepatic encephalopathy (MHE), which shows mild cognitive impairment, is a subtle complication of cirrhosis that has been shown to affect daily functioning and quality of life. However, until 2014, relevant guidelines do not give much attention to the diagnosis and treatment of MHE, resulting in patients being ignored and denied the benefits of treatment. In this review, we summarize recent cognition-based research about (1) alteration of nerve cells, including astrocytes, microglial cells and neurons, in mild cognitive impairment in MHE; (2) comparison of methods in detecting cognitive impairment in MHE; and (3) comparison of methods for therapy of cognitive impairment in MHE. We hope to provide information about diagnosis and treatment of cognitive impairment in patients with MHE. Springer US 2020-06-03 2020 /pmc/articles/PMC7354280/ /pubmed/32495311 http://dx.doi.org/10.1007/s11011-020-00539-w Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Review Article
Han, Weijia
Zhang, Huanqian
Han, Ying
Duan, Zhongping
Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
title Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
title_full Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
title_fullStr Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
title_full_unstemmed Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
title_short Cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
title_sort cognition-tracking-based strategies for diagnosis and treatment of minimal hepatic encephalopathy
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354280/
https://www.ncbi.nlm.nih.gov/pubmed/32495311
http://dx.doi.org/10.1007/s11011-020-00539-w
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