Loss of epithelial AR increase castration resistant stem-like prostate cancer cells and promotes cancer metastasis via TGF-β1/EMT pathway

BACKGROUND: Previous study has reported that loss of epithelial androgen receptor (AR) may promote tumor progression and cause TRAMP mouse model die earlier. The detail mechanisms, however, remain unclear. METHODS: Immunohistochemistry assay, Western blot and real-time PCR were used to detect the ex...

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Detalles Bibliográficos
Autores principales: Cai, Qiliang, Chen, Yegang, Zhang, Dingnrong, Pan, Jiancheng, Xie, Zunke, Ma, Shenze, Liu, Chuanfeng, Zuo, Jiquan, Zhou, Xiaodong, Quan, Changyi, Xin, Zhongcheng, Niu, Yuanjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354287/
https://www.ncbi.nlm.nih.gov/pubmed/32676386
http://dx.doi.org/10.21037/tau.2020.03.02

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