A single-centre experience of intravenous thrombolysis for stroke in COVID-19 patients

The sudden worldwide outbreak of Coronavirus Disease 2019 (COVID-19) has certainly provided new challenges in the management of acute ischaemic stroke, and the risk-benefit ratio of intravenous thrombolysis in COVID-19 positive patients is not well known. We describe four COVID-19 patients treated w...

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Detalles Bibliográficos
Autores principales: Sangalli, Davide, Polonia, Valeria, Colombo, Daniele, Mantero, Vittorio, Filizzolo, Marco, Scaccabarozzi, Chiara, Salmaggi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Covid-19
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354364/
https://www.ncbi.nlm.nih.gov/pubmed/32656711
http://dx.doi.org/10.1007/s10072-020-04591-3
Descripción
Sumario:The sudden worldwide outbreak of Coronavirus Disease 2019 (COVID-19) has certainly provided new challenges in the management of acute ischaemic stroke, and the risk-benefit ratio of intravenous thrombolysis in COVID-19 positive patients is not well known. We describe four COVID-19 patients treated with intravenous thrombolysis for acute ischaemic stroke. Although rt-PA administration is the main therapeutic strategy, our patients experienced unpredictable complications and showed atypical features: the overall mortality was very high. In conclusion, in this article, we provide information about these cases and discuss the possible explanation behind this trend.

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