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Liver fibrosis is driven by protease‐activated receptor‐1 expressed by hepatic stellate cells in experimental chronic liver injury

BACKGROUND: Blood coagulation protease activity is proposed to drive hepatic fibrosis through activation of protease‐activated receptors (PARs). Whole‐body PAR‐1 deficiency reduces experimental hepatic fibrosis, and in vitro studies suggest a potential contribution by PAR‐1 expressed by hepatic stel...

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Detalles Bibliográficos
Autores principales:	Poole, Lauren G., Pant, Asmita, Cline‐Fedewa, Holly M., Williams, Kurt J., Copple, Bryan L., Palumbo, Joseph S., Luyendyk, James P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles: Thrombosis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354391/ https://www.ncbi.nlm.nih.gov/pubmed/32685902 http://dx.doi.org/10.1002/rth2.12403

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