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An illustrated review of bleeding assessment tools and common coagulation tests
Recognizing the complexity of coagulation tests and currently used anticoagulants, we developed this illustrated review on bleeding assessment tools and common coagulation screening tests. Quantitative bleeding assessment tools (BATs) are available to standardize the bleeding history and improve the...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354401/ https://www.ncbi.nlm.nih.gov/pubmed/32685885 http://dx.doi.org/10.1002/rth2.12339 |
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author | Elbaz, Carolyne Sholzberg, Michelle |
author_facet | Elbaz, Carolyne Sholzberg, Michelle |
author_sort | Elbaz, Carolyne |
collection | PubMed |
description | Recognizing the complexity of coagulation tests and currently used anticoagulants, we developed this illustrated review on bleeding assessment tools and common coagulation screening tests. Quantitative bleeding assessment tools (BATs) are available to standardize the bleeding history and improve the pretest probability prior to coagulation testing. We describe use of BATs and the principles, indications, and limitations of the prothrombin time (PT)/International Normalized Ratio, activated partial thromboplastin time (APTT), and 50:50 mix. Use of these tests to identify coagulation factor deficiencies, specific and nonspecific inhibitors, coagulopathy of liver disease, disseminated intravascular coagulation, and commonly used anticoagulant medications are reviewed. Current literature suggests that unnecessary coagulation testing is rampant. The PT and APTT have astoundingly low sensitivity (1.0%‐2.1%) for detection of clinically significant bleeding disorders. Thus, current guidelines recommend against the use of screening PT and APTT in preoperative patients undergoing noncardiac/vascular surgery. |
format | Online Article Text |
id | pubmed-7354401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-73544012020-07-17 An illustrated review of bleeding assessment tools and common coagulation tests Elbaz, Carolyne Sholzberg, Michelle Res Pract Thromb Haemost Illustrated Review Recognizing the complexity of coagulation tests and currently used anticoagulants, we developed this illustrated review on bleeding assessment tools and common coagulation screening tests. Quantitative bleeding assessment tools (BATs) are available to standardize the bleeding history and improve the pretest probability prior to coagulation testing. We describe use of BATs and the principles, indications, and limitations of the prothrombin time (PT)/International Normalized Ratio, activated partial thromboplastin time (APTT), and 50:50 mix. Use of these tests to identify coagulation factor deficiencies, specific and nonspecific inhibitors, coagulopathy of liver disease, disseminated intravascular coagulation, and commonly used anticoagulant medications are reviewed. Current literature suggests that unnecessary coagulation testing is rampant. The PT and APTT have astoundingly low sensitivity (1.0%‐2.1%) for detection of clinically significant bleeding disorders. Thus, current guidelines recommend against the use of screening PT and APTT in preoperative patients undergoing noncardiac/vascular surgery. John Wiley and Sons Inc. 2020-07-06 /pmc/articles/PMC7354401/ /pubmed/32685885 http://dx.doi.org/10.1002/rth2.12339 Text en © 2020 The Authors. Research and Practice in Thrombosis and Haemostasis published by Wiley Periodicals LLC on behalf of International Society on Thrombosis and Haemostasis. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
spellingShingle | Illustrated Review Elbaz, Carolyne Sholzberg, Michelle An illustrated review of bleeding assessment tools and common coagulation tests |
title | An illustrated review of bleeding assessment tools and common coagulation tests |
title_full | An illustrated review of bleeding assessment tools and common coagulation tests |
title_fullStr | An illustrated review of bleeding assessment tools and common coagulation tests |
title_full_unstemmed | An illustrated review of bleeding assessment tools and common coagulation tests |
title_short | An illustrated review of bleeding assessment tools and common coagulation tests |
title_sort | illustrated review of bleeding assessment tools and common coagulation tests |
topic | Illustrated Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354401/ https://www.ncbi.nlm.nih.gov/pubmed/32685885 http://dx.doi.org/10.1002/rth2.12339 |
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