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Persistent Innate Immune Stimulation Results in IRF3-Mediated but Caspase-Independent Cytostasis

Persistent virus infection continuously produces non-self nucleic acids that activate cell-intrinsic immune responses. However, the antiviral defense evolved as a transient, acute phase response and the effects of persistently ongoing stimulation onto cellular homeostasis are not well understood. To...

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Detalles Bibliográficos
Autores principales:	Urban, Christian, Welsch, Hendrik, Heine, Katharina, Wüst, Sandra, Haas, Darya A., Dächert, Christopher, Pandey, Aparna, Pichlmair, Andreas, Binder, Marco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354422/ https://www.ncbi.nlm.nih.gov/pubmed/32545331 http://dx.doi.org/10.3390/v12060635

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