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Development and Application of Performance Assessment Criteria for Next-Generation Sequencing-Based HIV Drug Resistance Assays

Next-generation sequencing (NGS)-based HIV drug resistance (HIVDR) assays outperform conventional Sanger sequencing in scalability, sensitivity, and quantitative detection of minority resistance variants. Thus far, HIVDR assays have been applied primarily in research but rarely in clinical settings....

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Detalles Bibliográficos
Autores principales:	Becker, Michael G., Liang, Dun, Cooper, Breanna, Le, Yan, Taylor, Tracy, Lee, Emma R., Wu, Sutan, Sandstrom, Paul, Ji, Hezhao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354553/ https://www.ncbi.nlm.nih.gov/pubmed/32532083 http://dx.doi.org/10.3390/v12060627

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