Sevelamer Use in End-Stage Kidney Disease (ESKD) Patients Associates with Poor Vitamin K Status and High Levels of Gut-Derived Uremic Toxins: A Drug–Bug Interaction?

Gut microbial metabolism is not only an important source of uremic toxins but may also help to maintain the vitamin K stores of the host. We hypothesized that sevelamer therapy, a commonly used phosphate binder in patients with end-stage kidney disease (ESKD), associates with a disturbed gut microbi...

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Detalles Bibliográficos
Autores principales: Dai, Lu, Meijers, Björn K., Bammens, Bert, de Loor, Henriette, Schurgers, Leon J., Qureshi, Abdul Rashid, Stenvinkel, Peter, Evenepoel, Pieter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354623/
https://www.ncbi.nlm.nih.gov/pubmed/32471179
http://dx.doi.org/10.3390/toxins12060351

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