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Blockade of Adenosine A(2A) Receptor Protects Photoreceptors after Retinal Detachment by Inhibiting Inflammation and Oxidative Stress

PURPOSE: Adenosine A(2A) receptor (A(2A)R) signaling is neuroprotective in some retinal damage models, but its role in neuronal survival during retinal detachment (RD) is unclear. We tested the hypothesis that A(2A)R antagonist ZM241385 would prevent photoreceptor apoptosis by inhibiting retinal inf...

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Detalles Bibliográficos
Autores principales:	Gao, Sha, Li, Na, Wang, Yanuo, Zhong, Yisheng, Shen, Xi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354651/ https://www.ncbi.nlm.nih.gov/pubmed/32714489 http://dx.doi.org/10.1155/2020/7649080

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