Muscle‐specific sirtuin1 gain‐of‐function ameliorates skeletal muscle atrophy in a pre‐clinical mouse model of cerebral ischemic stroke

Stroke causes severe long‐term disability in patients due to the induction of skeletal muscle atrophy and weakness, but the molecular mechanisms remain elusive. Using a preclinical mouse model of cerebral ischemic stroke, we show that stroke robustly induced atrophy and significantly decreased SirT1...

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Detalles Bibliográficos
Autores principales: Tuntevski, Kiril, Hajira, Ameena, Nichols, Austin, Alway, Stephen E., Mohamed, Junaith S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354693/
https://www.ncbi.nlm.nih.gov/pubmed/32676579
http://dx.doi.org/10.1096/fba.2020-00017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354693/
https://www.ncbi.nlm.nih.gov/pubmed/32676579
http://dx.doi.org/10.1096/fba.2020-00017

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