Cargando…
Metabolic response of Insulinoma 1E cells to glucose stimulation studied by fluorescence lifetime imaging
A cascade of highly regulated biochemical processes connects glucose stimulation to insulin secretion in specialized cells of mammalian pancreas, the β‐cells. Given the importance of this process for systemic glucose homeostasis, noninvasive and fast strategies capable to monitor the response to glu...
Autores principales: | Ferri, Gianmarco, Tesi, Marta, Massarelli, Federico, Marselli, Lorella, Marchetti, Piero, Cardarelli, Francesco |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354695/ https://www.ncbi.nlm.nih.gov/pubmed/32676581 http://dx.doi.org/10.1096/fba.2020-00014 |
Ejemplares similares
-
Spatiotemporal Correlation Spectroscopy Reveals a Protective Effect of Peptide-Based GLP-1 Receptor Agonism against Lipotoxicity on Insulin Granule Dynamics in Primary Human β-Cells
por: Ferri, Gianmarco, et al.
Publicado: (2021) -
β-Cell Pathophysiology: A Review of Advanced Optical Microscopy Applications
por: Ferri, Gianmarco, et al.
Publicado: (2021) -
Single-cell imaging of α and β cell metabolic response to glucose in living human Langerhans islets
por: Azzarello, Fabio, et al.
Publicado: (2022) -
Pro-Inflammatory Cytokines Induce Insulin and Glucagon Double Positive Human Islet Cells That Are Resistant to Apoptosis
por: Tesi, Marta, et al.
Publicado: (2021) -
Insulin secretory granules labelled with phogrin-fluorescent proteins show alterations in size, mobility and responsiveness to glucose stimulation in living β-cells
por: Ferri, Gianmarco, et al.
Publicado: (2019)