Sam68 mediates leptin signaling and action in human granulosa cells: possible role in leptin resistance in PCOS

INTRODUCTION: Polycystic ovary syndrome (PCOS) is a complex metabolic disorder associated with ovulatory dysfunction, hyperandrogenism, obesity, and insulin resistance, that leads to subfertility. Sam68 is an RNA-binding protein with signaling functions that is ubiquitously expressed, including gona...

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Detalles Bibliográficos
Autores principales: Vilariño-García, Teresa, Pérez-Pérez, Antonio, Santamaría-López, Esther, Prados, Nicolás, Fernández-Sánchez, Manuel, Sánchez-Margalet, Víctor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354740/
https://www.ncbi.nlm.nih.gov/pubmed/32375121
http://dx.doi.org/10.1530/EC-20-0062

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