Safety and Biocompatibility of Aflibercept-Loaded Microsphere Thermo-Responsive Hydrogel Drug Delivery System in a Nonhuman Primate Model

PURPOSE: To evaluate the safety and tolerability of a microsphere thermo-responsive hydrogel drug delivery system (DDS) loaded with aflibercept in a nonhuman primate model. METHODS: A sterile 50 µL of aflibercept-loaded microsphere thermo-responsive hydrogel-DDS (aflibercept-DDS) was injected intrav...

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Detalles Bibliográficos
Autores principales: Kim, Soohyun, Kang-Mieler, Jennifer J., Liu, Wenqiang, Wang, Zhe, Yiu, Glenn, Teixeira, Leandro B. C., Mieler, William F., Thomasy, Sara M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354880/
https://www.ncbi.nlm.nih.gov/pubmed/32742760
http://dx.doi.org/10.1167/tvst.9.3.30

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