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Pervasive changes of mRNA splicing in upf1-deficient zebrafish identify rpl10a as a regulator of T cell development

The transcriptome of eukaryotic cells is constantly monitored for errors to avoid the production of undesired protein variants. The evolutionarily conserved nonsense-mediated mRNA decay (NMD) pathway degrades aberrant mRNAs, but also functions in the regulation of transcript abundance in response to...

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Detalles Bibliográficos
Autores principales:	Lawir, Divine-Fondzenyuy, Sikora, Katarzyna, O’Meara, Connor P., Schorpp, Michael, Boehm, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	National Academy of Sciences 2020
Materias:	Biological Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7354994/ https://www.ncbi.nlm.nih.gov/pubmed/32571908 http://dx.doi.org/10.1073/pnas.1917812117

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