Modeling Hypoxia-Induced Neuropathies Using a Fast and Scalable Human Motor Neuron Differentiation System

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Human motor neuron (MN) diseases encompass a spectrum of disorders. A critical barrier to dissecting disease mechanisms is the lack of appropriate human MN models. Here, we describe a scalable, suspension-based differentiation system to generate functional human MN diseases in 3 weeks. Using this mo...

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Detalles Bibliográficos
Autores principales: Hudish, Laura I., Bubak, Andrew, Triolo, Taylor M., Niemeyer, Christy S., Sussel, Lori, Nagel, Maria, Taliaferro, J. Matthew, Russ, Holger A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355142/
https://www.ncbi.nlm.nih.gov/pubmed/32386561
http://dx.doi.org/10.1016/j.stemcr.2020.04.003
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