The locality dilemma of Sankoff-like RNA alignments

MOTIVATION: Elucidating the functions of non-coding RNAs by homology has been strongly limited due to fundamental computational and modeling issues. While existing simultaneous alignment and folding (SA&F) algorithms successfully align homologous RNAs with precisely known boundaries (global SA&a...

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Detalles Bibliográficos
Autores principales: Müller, Teresa, Miladi, Milad, Hutter, Frank, Hofacker, Ivo, Will, Sebastian, Backofen, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Macromolecular Sequence, Structure, and Function
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355259/
https://www.ncbi.nlm.nih.gov/pubmed/32657398
http://dx.doi.org/10.1093/bioinformatics/btaa431

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355259/
https://www.ncbi.nlm.nih.gov/pubmed/32657398
http://dx.doi.org/10.1093/bioinformatics/btaa431

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