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Robust and accurate deconvolution of tumor populations uncovers evolutionary mechanisms of breast cancer metastasis

MOTIVATION: Cancer develops and progresses through a clonal evolutionary process. Understanding progression to metastasis is of particular clinical importance, but is not easily analyzed by recent methods because it generally requires studying samples gathered years apart, for which modern single-ce...

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Detalles Bibliográficos
Autores principales:	Tao, Yifeng, Lei, Haoyun, Fu, Xuecong, Lee, Adrian V, Ma, Jian, Schwartz, Russell
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2020
Materias:	Studies of Phenotypes and Clinical Applications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355293/ https://www.ncbi.nlm.nih.gov/pubmed/32657393 http://dx.doi.org/10.1093/bioinformatics/btaa396

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