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Chrysophanol Prevents Lipopolysaccharide-Induced Hepatic Stellate Cell Activation by Upregulating Apoptosis, Oxidative Stress, and the Unfolded Protein Response

Hepatic stellate cell (HSC) activation is a vital driver of liver fibrosis. Recent research efforts have emphasized the clearance of activated HSCs by apoptosis, senescence, or reversion to the quiescent state. LPS induces human HSC activation directly and contributes to liver disease progression. C...

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Detalles Bibliográficos
Autores principales:	Wu, Jiunn-Sheng, Chiu, Valeria, Lan, Chou-Chin, Wang, Ming-Chieh, Tzeng, I.-Shiang, Kuo, Chan-Yen, Hsieh, Po-Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355365/ https://www.ncbi.nlm.nih.gov/pubmed/32714424 http://dx.doi.org/10.1155/2020/8426051

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