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A Lipidomic Perspective of the Action of Group IIA Secreted Phospholipase A(2) on Human Monocytes: Lipid Droplet Biogenesis and Activation of Cytosolic Phospholipase A(2)α
Phospholipase A(2)s constitute a wide group of lipid-modifying enzymes which display a variety of functions in innate immune responses. In this work, we utilized mass spectrometry-based lipidomic approaches to investigate the action of Asp-49 Ca(2+)-dependent secreted phospholipase A(2) (sPLA(2)) (M...
Autores principales: | Rodríguez, Juan P., Leiguez, Elbio, Guijas, Carlos, Lomonte, Bruno, Gutiérrez, José M., Teixeira, Catarina, Balboa, María A., Balsinde, Jesús |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355433/ https://www.ncbi.nlm.nih.gov/pubmed/32532115 http://dx.doi.org/10.3390/biom10060891 |
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