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The (+)-Brevipolide H Displays Anticancer Activity against Human Castration-Resistant Prostate Cancer: The Role of Oxidative Stress and Akt/mTOR/p70S6K-Dependent Pathways in G1 Checkpoint Arrest and Apoptosis

Because conventional chemotherapy is not sufficiently effective against prostate cancer, various examinations have been performed to identify anticancer activity of naturally occurring components and their mechanisms of action. The (+)-brevipolide H, an α-pyrone-based natural compound, induced poten...

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Detalles Bibliográficos
Autores principales:	Sheng, Yi-Hua, Leu, Wohn-Jenn, Chen, Ching-Nung, Hsu, Jui-Ling, Liu, Ying-Tung, Hsu, Lih-Ching, Hou, Duen-Ren, Guh, Jih-Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355498/ https://www.ncbi.nlm.nih.gov/pubmed/32630532 http://dx.doi.org/10.3390/molecules25122929

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