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A Doxorubicin-Glucuronide Prodrug Released from Nanogels Activated by High-Intensity Focused Ultrasound Liberated β-Glucuronidase

The poor pharmacokinetics and selectivity of low-molecular-weight anticancer drugs contribute to the relatively low effectiveness of chemotherapy treatments. To improve the pharmacokinetics and selectivity of these treatments, the combination of a doxorubicin-glucuronide prodrug (DOX-propGA3) nanoge...

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Detalles Bibliográficos
Autores principales:	Besse, Helena C., Chen, Yinan, Scheeren, Hans W., Metselaar, Josbert M., Lammers, Twan, Moonen, Chrit T. W., Hennink, Wim E., Deckers, Roel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355552/ https://www.ncbi.nlm.nih.gov/pubmed/32532061 http://dx.doi.org/10.3390/pharmaceutics12060536

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