Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care

The development of new HER2-directed therapies has resulted in a significant prolongation of survival for women with metastatic HER2-positive breast cancer. Discoveries in the laboratory inform clinical trials which are the basis for improving the standard of care and are also the backbone for quali...

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Autores principales: Mortimer, Joanne E., Kruper, Laura, Cianfrocca, Mary, Lavasani, Sayeh, Liu, Sariah, Tank-Patel, Niki, Sedrak, Mina, Smith, Wade, Stewart, Daphne, Waisman, James, Yeon, Christina, Wang, Tina, Yuan, Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355741/
https://www.ncbi.nlm.nih.gov/pubmed/32599960
http://dx.doi.org/10.3390/jcm9061984
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author Mortimer, Joanne E.
Kruper, Laura
Cianfrocca, Mary
Lavasani, Sayeh
Liu, Sariah
Tank-Patel, Niki
Sedrak, Mina
Smith, Wade
Stewart, Daphne
Waisman, James
Yeon, Christina
Wang, Tina
Yuan, Yuan
author_facet Mortimer, Joanne E.
Kruper, Laura
Cianfrocca, Mary
Lavasani, Sayeh
Liu, Sariah
Tank-Patel, Niki
Sedrak, Mina
Smith, Wade
Stewart, Daphne
Waisman, James
Yeon, Christina
Wang, Tina
Yuan, Yuan
author_sort Mortimer, Joanne E.
collection PubMed
description The development of new HER2-directed therapies has resulted in a significant prolongation of survival for women with metastatic HER2-positive breast cancer. Discoveries in the laboratory inform clinical trials which are the basis for improving the standard of care and are also the backbone for quality improvement. Clinical trials can be completed more rapidly by expanding trial enrollment to community sites. In this article we review some of the challenges in treating metastatic breast cancer with HER2-directed therapies and our strategies for incorporating our community partners into the research network.
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spelling pubmed-73557412020-07-23 Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care Mortimer, Joanne E. Kruper, Laura Cianfrocca, Mary Lavasani, Sayeh Liu, Sariah Tank-Patel, Niki Sedrak, Mina Smith, Wade Stewart, Daphne Waisman, James Yeon, Christina Wang, Tina Yuan, Yuan J Clin Med Article The development of new HER2-directed therapies has resulted in a significant prolongation of survival for women with metastatic HER2-positive breast cancer. Discoveries in the laboratory inform clinical trials which are the basis for improving the standard of care and are also the backbone for quality improvement. Clinical trials can be completed more rapidly by expanding trial enrollment to community sites. In this article we review some of the challenges in treating metastatic breast cancer with HER2-directed therapies and our strategies for incorporating our community partners into the research network. MDPI 2020-06-24 /pmc/articles/PMC7355741/ /pubmed/32599960 http://dx.doi.org/10.3390/jcm9061984 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mortimer, Joanne E.
Kruper, Laura
Cianfrocca, Mary
Lavasani, Sayeh
Liu, Sariah
Tank-Patel, Niki
Sedrak, Mina
Smith, Wade
Stewart, Daphne
Waisman, James
Yeon, Christina
Wang, Tina
Yuan, Yuan
Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care
title Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care
title_full Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care
title_fullStr Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care
title_full_unstemmed Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care
title_short Use of HER2-Directed Therapy in Metastatic Breast Cancer and How Community Physicians Collaborate to Improve Care
title_sort use of her2-directed therapy in metastatic breast cancer and how community physicians collaborate to improve care
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355741/
https://www.ncbi.nlm.nih.gov/pubmed/32599960
http://dx.doi.org/10.3390/jcm9061984
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