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Elucidation of Inverse Agonist Activity of Bilastine

H(1)-antihistamines antagonize histamine and prevent it from binding to the histamine H(1) receptor (H1R). Some of them also act as inverse agonists, which are more potent than pure antagonists because they suppress the constitutive H1R activity. Bilastine is a non-sedative antihistamine which is on...

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Detalles Bibliográficos
Autores principales:	Mizuguchi, Hiroyuki, Wakugawa, Tomoharu, Sadakata, Hisato, Kamimura, Seiichiro, Takemoto, Mai, Nakagawa, Tomomi, Yabumoto, Masami, Kitamura, Yoshiaki, Takeda, Noriaki, Fukui, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355758/ https://www.ncbi.nlm.nih.gov/pubmed/32521742 http://dx.doi.org/10.3390/pharmaceutics12060525

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