Cargando…
Treatment with a New Barbituric Acid Derivative Exerts Antiproliferative and Antimigratory Effects against Sorafenib Resistance in Hepatocellular Carcinoma
Hepatocellular carcinoma (HCC) is a common cause of cancer death worldwide. Sorafenib, a multikinase inhibitor, is the first-line drug approved by the Food and Drug Administration (FDA) for the treatment of patients with advanced HCC. However, most patients who continuously receive sorafenib may acq...
Autores principales: | Liao, Yi-Jen, Hsu, Shih-Ming, Chien, Chia-Ying, Wang, Yuan-Hsi, Hsu, Ming-Hua, Suk, Fat-Moon |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355767/ https://www.ncbi.nlm.nih.gov/pubmed/32575795 http://dx.doi.org/10.3390/molecules25122856 |
Ejemplares similares
-
Antifibrotic Effects of a Barbituric Acid Derivative on Liver Fibrosis by Blocking the NF-κB Signaling Pathway in Hepatic Stellate Cells
por: Wang, Yuan-Hsi, et al.
Publicado: (2020) -
Treatment with a new benzimidazole derivative bearing a pyrrolidine side chain overcomes sorafenib resistance in hepatocellular carcinoma
por: Suk, Fat-Moon, et al.
Publicado: (2019) -
Secretory NPC2 Protein-Mediated Free Cholesterol Levels Were Correlated with the Sorafenib Response in Hepatocellular Carcinoma
por: Suk, Fat-Moon, et al.
Publicado: (2021) -
Antiproliferative and antimigratory activities of bisphosphonates in human breast cancer cell line MCF-7
por: Buranrat, Benjaporn, et al.
Publicado: (2019) -
Barbiturate- and Thiobarbituarte-Based s-Triazine
Hydrazone Derivatives with Promising Antiproliferative
Activities
por: Al Rasheed, Hessa, et al.
Publicado: (2020)