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Vaccines and Therapies in Development for SARS-CoV-2 Infections

The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths reported. Given the current severity of the outbreak, there is a...

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Detalles Bibliográficos
Autores principales: Wu, David, Koganti, Raghuram, Lambe, Upendra P., Yadavalli, Tejabhiram, Nandi, Shyam S., Shukla, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355822/
https://www.ncbi.nlm.nih.gov/pubmed/32560227
http://dx.doi.org/10.3390/jcm9061885
Descripción
Sumario:The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths reported. Given the current severity of the outbreak, there is a great need for antiviral therapies and vaccines to treat and prevent COVID-19. In this review, we provide an overview of SARS-CoV-2 and discuss the emerging therapies and vaccines that show promise in combating COVID-19. We also highlight potential viral targets that could be exploited by researchers and drug manufacturers.