Vaccines and Therapies in Development for SARS-CoV-2 Infections

The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths reported. Given the current severity of the outbreak, there is a...

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Autores principales: Wu, David, Koganti, Raghuram, Lambe, Upendra P., Yadavalli, Tejabhiram, Nandi, Shyam S., Shukla, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355822/
https://www.ncbi.nlm.nih.gov/pubmed/32560227
http://dx.doi.org/10.3390/jcm9061885
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author Wu, David
Koganti, Raghuram
Lambe, Upendra P.
Yadavalli, Tejabhiram
Nandi, Shyam S.
Shukla, Deepak
author_facet Wu, David
Koganti, Raghuram
Lambe, Upendra P.
Yadavalli, Tejabhiram
Nandi, Shyam S.
Shukla, Deepak
author_sort Wu, David
collection PubMed
description The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths reported. Given the current severity of the outbreak, there is a great need for antiviral therapies and vaccines to treat and prevent COVID-19. In this review, we provide an overview of SARS-CoV-2 and discuss the emerging therapies and vaccines that show promise in combating COVID-19. We also highlight potential viral targets that could be exploited by researchers and drug manufacturers.
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spelling pubmed-73558222020-07-23 Vaccines and Therapies in Development for SARS-CoV-2 Infections Wu, David Koganti, Raghuram Lambe, Upendra P. Yadavalli, Tejabhiram Nandi, Shyam S. Shukla, Deepak J Clin Med Review The current COVID-19 pandemic is caused by the novel coronavirus SARS-CoV-2. The virus causes severe respiratory symptoms which manifest disproportionately in the elderly. Currently, there are over 6.5 million cases and 380,000 deaths reported. Given the current severity of the outbreak, there is a great need for antiviral therapies and vaccines to treat and prevent COVID-19. In this review, we provide an overview of SARS-CoV-2 and discuss the emerging therapies and vaccines that show promise in combating COVID-19. We also highlight potential viral targets that could be exploited by researchers and drug manufacturers. MDPI 2020-06-16 /pmc/articles/PMC7355822/ /pubmed/32560227 http://dx.doi.org/10.3390/jcm9061885 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Wu, David
Koganti, Raghuram
Lambe, Upendra P.
Yadavalli, Tejabhiram
Nandi, Shyam S.
Shukla, Deepak
Vaccines and Therapies in Development for SARS-CoV-2 Infections
title Vaccines and Therapies in Development for SARS-CoV-2 Infections
title_full Vaccines and Therapies in Development for SARS-CoV-2 Infections
title_fullStr Vaccines and Therapies in Development for SARS-CoV-2 Infections
title_full_unstemmed Vaccines and Therapies in Development for SARS-CoV-2 Infections
title_short Vaccines and Therapies in Development for SARS-CoV-2 Infections
title_sort vaccines and therapies in development for sars-cov-2 infections
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355822/
https://www.ncbi.nlm.nih.gov/pubmed/32560227
http://dx.doi.org/10.3390/jcm9061885
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