Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)

The Centers for Disease Control declared e-cigarette, or vaping, product use-associated lung injury (EVALI) a national outbreak due to the high incidence of emergency department admissions and deaths. We have identified chemical constituents in e-cig counterfeit cartridges and compared these to medi...

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Autores principales: Muthumalage, Thivanka, Friedman, Michelle R., McGraw, Matthew D., Ginsberg, Gary, Friedman, Alan E., Rahman, Irfan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355865/
https://www.ncbi.nlm.nih.gov/pubmed/32260052
http://dx.doi.org/10.3390/toxics8020025
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author Muthumalage, Thivanka
Friedman, Michelle R.
McGraw, Matthew D.
Ginsberg, Gary
Friedman, Alan E.
Rahman, Irfan
author_facet Muthumalage, Thivanka
Friedman, Michelle R.
McGraw, Matthew D.
Ginsberg, Gary
Friedman, Alan E.
Rahman, Irfan
author_sort Muthumalage, Thivanka
collection PubMed
description The Centers for Disease Control declared e-cigarette, or vaping, product use-associated lung injury (EVALI) a national outbreak due to the high incidence of emergency department admissions and deaths. We have identified chemical constituents in e-cig counterfeit cartridges and compared these to medical-grade and CBD containing cartridges. Apart from vitamin E acetate (VEA) and tetrahydrocannabinol (THC), other potential toxicants were identified including solvent-derived hydrocarbons, silicon conjugated compounds, various terpenes, pesticides/plasticizers/polycaprolactones, and metals. This study provides additional insights into the chemicals associated with EVALI cartridges and thus may contribute to the underlying disease mechanism of acute lung injury.
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spelling pubmed-73558652020-07-23 Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI) Muthumalage, Thivanka Friedman, Michelle R. McGraw, Matthew D. Ginsberg, Gary Friedman, Alan E. Rahman, Irfan Toxics Article The Centers for Disease Control declared e-cigarette, or vaping, product use-associated lung injury (EVALI) a national outbreak due to the high incidence of emergency department admissions and deaths. We have identified chemical constituents in e-cig counterfeit cartridges and compared these to medical-grade and CBD containing cartridges. Apart from vitamin E acetate (VEA) and tetrahydrocannabinol (THC), other potential toxicants were identified including solvent-derived hydrocarbons, silicon conjugated compounds, various terpenes, pesticides/plasticizers/polycaprolactones, and metals. This study provides additional insights into the chemicals associated with EVALI cartridges and thus may contribute to the underlying disease mechanism of acute lung injury. MDPI 2020-04-03 /pmc/articles/PMC7355865/ /pubmed/32260052 http://dx.doi.org/10.3390/toxics8020025 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Muthumalage, Thivanka
Friedman, Michelle R.
McGraw, Matthew D.
Ginsberg, Gary
Friedman, Alan E.
Rahman, Irfan
Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)
title Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)
title_full Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)
title_fullStr Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)
title_full_unstemmed Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)
title_short Chemical Constituents Involved in E-Cigarette, or Vaping Product Use-Associated Lung Injury (EVALI)
title_sort chemical constituents involved in e-cigarette, or vaping product use-associated lung injury (evali)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355865/
https://www.ncbi.nlm.nih.gov/pubmed/32260052
http://dx.doi.org/10.3390/toxics8020025
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