The Anti-Diabetic Drug Metformin Rescues Aberrant Mitochondrial Activity and Restrains Oxidative Stress in a Female Mouse Model of Rett Syndrome

Metformin is the first-line therapy for diabetes, even in children, and a promising attractive candidate for drug repurposing. Mitochondria are emerging as crucial targets of metformin action both in the periphery and in the brain. The present study evaluated whether treatment with metformin may res...

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Detalles Bibliográficos
Autores principales: Zuliani, Ilaria, Urbinati, Chiara, Valenti, Daniela, Quattrini, Maria Cristina, Medici, Vanessa, Cosentino, Livia, Pietraforte, Donatella, Di Domenico, Fabio, Perluigi, Marzia, Vacca, Rosa Anna, De Filippis, Bianca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355965/
https://www.ncbi.nlm.nih.gov/pubmed/32492904
http://dx.doi.org/10.3390/jcm9061669

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