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Nano-Polyplexes Mediated Transfection of Runx2-shRNA Mitigates the Osteodifferentiation of Human Valvular Interstitial Cells

Calcific aortic valve disease (CAVD) is a progressive disorder that increases in prevalence with age. An important role in aortic valve calcification is played by valvular interstitial cells (VIC), that with age or in pathological conditions acquire an osteoblast-like phenotype that advances the dis...

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Detalles Bibliográficos
Autores principales:	Voicu, Geanina, Rebleanu, Daniela, Constantinescu, Cristina Ana, Fuior, Elena Valeria, Ciortan, Letitia, Droc, Ionel, Uritu, Cristina Mariana, Pinteala, Mariana, Manduteanu, Ileana, Simionescu, Maya, Calin, Manuela
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7355966/ https://www.ncbi.nlm.nih.gov/pubmed/32498305 http://dx.doi.org/10.3390/pharmaceutics12060507

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