Carbamoyl-Phosphate Synthase 1 as a Novel Target of Phomoxanthone A, a Bioactive Fungal Metabolite

Phomoxanthone A, a bioactive xanthone dimer isolated from the endophytic fungus Phomopsis sp., is a mitochondrial toxin weakening cellular respiration and electron transport chain activity by a fast breakup of the mitochondrial assembly. Here, a multi-disciplinary strategy has been developed and app...

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Detalles Bibliográficos
Autores principales: Ceccacci, Sara, Deitersen, Jana, Mozzicafreddo, Matteo, Morretta, Elva, Proksch, Peter, Wesselborg, Sebastian, Stork, Björn, Monti, Maria Chiara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356042/
https://www.ncbi.nlm.nih.gov/pubmed/32498414
http://dx.doi.org/10.3390/biom10060846

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356042/
https://www.ncbi.nlm.nih.gov/pubmed/32498414
http://dx.doi.org/10.3390/biom10060846

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