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Oral Administration of Artemisone for the Treatment of Schistosomiasis: Formulation Challenges and In Vivo Efficacy

Artemisone is an innovative artemisinin derivative with applications in the treatment of malaria, schistosomiasis and other diseases. However, its low aqueous solubility and tendency to degrade after solubilisation limits the translation of this drug into clinical practice. We developed a self-micro...

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Detalles Bibliográficos
Autores principales: Zech, Johanna, Gold, Daniel, Salaymeh, Nadeen, Sasson, Netanel Cohen, Rabinowitch, Ithai, Golenser, Jacob, Mäder, Karsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356104/
https://www.ncbi.nlm.nih.gov/pubmed/32503130
http://dx.doi.org/10.3390/pharmaceutics12060509