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Oral Administration of Artemisone for the Treatment of Schistosomiasis: Formulation Challenges and In Vivo Efficacy
Artemisone is an innovative artemisinin derivative with applications in the treatment of malaria, schistosomiasis and other diseases. However, its low aqueous solubility and tendency to degrade after solubilisation limits the translation of this drug into clinical practice. We developed a self-micro...
Autores principales: | Zech, Johanna, Gold, Daniel, Salaymeh, Nadeen, Sasson, Netanel Cohen, Rabinowitch, Ithai, Golenser, Jacob, Mäder, Karsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356104/ https://www.ncbi.nlm.nih.gov/pubmed/32503130 http://dx.doi.org/10.3390/pharmaceutics12060509 |
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