Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights from Combined Molecular Dynamics Simulations and Experimental Data

The freeze-drying of complex formulations, such as liposomes, is challenging, particularly if dispersions contain residual organic solvents. This work aimed to investigate the effects of possible protectants, namely sucrose, trehalose and/or poly(vinyl pyrrolidone) (PVP), on the main features of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Franzè, Silvia, Selmin, Francesca, Rocco, Paolo, Colombo, Giuseppe, Casiraghi, Antonella, Cilurzo, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356173/
https://www.ncbi.nlm.nih.gov/pubmed/32526935
http://dx.doi.org/10.3390/pharmaceutics12060530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356173/
https://www.ncbi.nlm.nih.gov/pubmed/32526935
http://dx.doi.org/10.3390/pharmaceutics12060530

Ejemplares similares