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Preserving the Integrity of Liposomes Prepared by Ethanol Injection upon Freeze-Drying: Insights from Combined Molecular Dynamics Simulations and Experimental Data

The freeze-drying of complex formulations, such as liposomes, is challenging, particularly if dispersions contain residual organic solvents. This work aimed to investigate the effects of possible protectants, namely sucrose, trehalose and/or poly(vinyl pyrrolidone) (PVP), on the main features of the...

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Detalles Bibliográficos
Autores principales:	Franzè, Silvia, Selmin, Francesca, Rocco, Paolo, Colombo, Giuseppe, Casiraghi, Antonella, Cilurzo, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7356173/ https://www.ncbi.nlm.nih.gov/pubmed/32526935 http://dx.doi.org/10.3390/pharmaceutics12060530

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